Turning Biological Complexity
into Precise Decision
Human-Relevant Models. Actionable Insights. Better Decisions.
We combine proprietary TME-Chip technology with deep expertise in oncology drug development, translational research, biomarker strategy, and multi-omics integration.
We partner with biopharmaceutical companies, academic medical centers, translational research laboratories, and clinical investigators to generate biologically relevant data and actionable insights that support drug development and precision oncology programs.
OUR PRODUCTS
Tumor Microenvironment Chip (TME-Chip)
Recreating the Tumor Microenvironment for Predictive Oncology Research
Pythia’s propriety TME-Chip combines 3D culture, dynamic perfusion, and compartmentalized tumor–stroma–immune interactions to recreate key features of the human tumor microenvironment. The platform supports drug penetration studies, immune migration analysis, real-time imaging, media sampling, and biomarker discovery to generate translationally relevant data for predictive oncology research.
KEY FEATURES
3D Culture
Supports tumor spheroids, organoids, and multicellular co-culture models to better mimic the architecture of human tumors.
Dynamic Perfusion
The central perfusion channel provides a stable and controlled flow environment, simulating nutrient delivery, metabolite exchange, and drug transport found in vivo.
Tumor-Stroma-Immune Interactioin
Recreates cellular crosstalk within the tumor microenvironment, enabling the study of immune responses and tumor biology.
Real-time Quantitative Analysis
Monitor treatment responses through live imaging, media sampling, and biochemical assays, enabling dynamic assessment of cellular behavior and therapeutic effects.
TME-Chip Perfusion Hub
Six TME-Chips. One Smart Controller.
A user-friendly perfusion platform designed to deliver physiologically relevant flow, scalable parallel experimentation, and automated control for tumor microenvironment research.
KEY FEATURES
PARALLEL PERFUSION
Run up to 6 TME-Chips simultaneously for control, treatment and combination studies.
PRECISE FLOW CONTROL
Integrated controlled enables precise flow rate and customizable perfusion profiles.
BUILT FOR TRANSLATION
Designed for oncology drug discovery, immunotherapy evaluation, ADC studies, and patient-derived models.
USER-FRIENDLY DESIGN
Intuitive setup and compact footprint for both academic, translational and biopharma environment
ADAPTABLE CHIP HOLDERS
Supports different chip formats with compatible holders.
Controller
Two pumps. Individual protocols. One touchscreen.
The Pythia Programmable Dual-Pump Flow Controller enables precise, programmable flow control for microfluidic perfusion and organ-on-chip experiments. It independently controls two compatible pumps, allowing researchers to create and run customized flow protocols through an intuitive touchscreen interface.
Independent operation of two pumps
Run different programs concurrently, starting and managing each pump from its own control card.
Flexible sequence editing
Combine TIMED steps with defined rate, direction, and duration, and WAIT steps that hold the pump stationary.
Repeatable step groups
Use loops to repeat selected steps without duplicating the sequence in the editor.
Shared Program Library
Save named protocols, load them to either pump, and import an independent copy for modification.
Pump-specific calibration
Use guided three-point calibration, with separate values for each pump and calibration available for both rotation directions.
Clear run status
View the active step, loop count, remaining program time, and volume counter for each pump
Contact Us
Connect with Pythia Biotech to learn more about our products and services,
explore partnering opportunities, or discuss potential collaborations.
